BDBM123850 US8748608, 34::US8748608, 34 Enantiomer A::US8748608, 34 Enantiomer B
SMILES OC(CCNC(=O)c1cc2ccccc2[nH]1)CN1CCN(CC1)c1cccc(Cl)c1Cl
InChI Key InChIKey=NABHHUMHJIHHIX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 123850
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 0.900nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.10nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in human HEK293 cell membrane for 1 hr by liquid scintillation counti...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 16.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair